In September 2025, a class action lawsuit was filed against Pfizer over allegations that the Depo-Provera birth control shot could cause women to develop meningioma brain tumors. 

The lawsuit alleges that women who used the Depo shot were not adequately warned about these risks, despite growing scientific evidence linking long-term use of the drug to tumors. 

If you used Depo-Provera and were later diagnosed with meningioma brain tumors, contact the lawyers at Hissey Mulderig & Friend to find out whether you qualify to take legal action, or start your claim today.  

You can reach us by calling our office toll-free at 1-866-806-8117, or send us a message online using our free case evaluation form, located on the right side of this page. 

Depo-Provera Lawsuits Expanding Quickly Nationwide

The September 2025 class action filing is part of a rapidly growing wave of litigation involving Depo-Provera.  

More than 1,400 lawsuits have already been filed in the United States. Legal experts have predicted that this number will continue to rise as more women become aware of the link between the Depo shot and meningioma brain tumors. 

The central claim in the Depo-Provera litigation is that Pfizer failed to adequately warn patients and doctors about the risk of developing meningioma brain tumors. 

Specifically, the lawsuits allege that: 

• Pfizer knew or should have known about the link between Depo-Provera and meningiomas  
• Long-term use of the drug significantly increases the risk of these tumors  
• Warnings provided to patients and physicians were insufficient  
• Earlier disclosure could have led women to choose different contraceptive options  

Scientific Evidence Linking Depo-Provera and Meningiomas

The allegations in the Depo-Provera class action are based on a growing body of scientific research linking the birth control shot to an increased risk of brain tumors.  

A 2024 study published in the British Medical Journal reported that prolonged use of Depo-Provera was associated with a significantly increased risk of intracranial meningiomas. 

A second study published by Expert Opinion on Drug Safety in January 2025 found that Depo-Provera users have a “substantially increased risk” developing meningioma compared to women who used birth control pills.  

The growing body of scientific evidence linking Depo-Provera to an increased risk of meningioma brain tumors prompted the FDA to issue a warning about the birth control shot in January 2026.  

The FDA warning confirmed that Depo-Provera users have a higher risk of meningioma brain tumors, and warned that women who use the birth control shot may require lifetime medical monitoring to check for signs of a brain tumor.  

What Is a Meningioma and Why It Matters for Depo Users

Meningiomas are a type of benign brain tumors that form in the membranes surrounding the brain and spinal cord. Although these tumors are not cancerous, they can still cause serious and life-altering complications. 

Symptoms of cerebral meningioma may include: 

• Chronic headaches  
• Vision problems  
• Seizures  
• Hearing loss  
• Cognitive or personality changes  

Treatment frequently involves brain surgery or radiation therapy, both of which carry substantial risks and long-term consequences. 

Who May Be Eligible to File a Depo-Provera Lawsuit

Women who experienced serious side effects after using Depo-Provera may qualify to file a claim if their situation meets certain criteria, including: 

1. Use of Depo-Provera or generic medroxyprogesterone injections  
2. Diagnosed with meningioma brain tumors after starting the Depo shot  
3. At least one year of use, which typically means four shots 

If you or a loved one meet all of the above criteria, contact the birth control attorneys at Hissey Mulderig & Friend to find out more about whether you may qualify to take legal action and to start the process of filing your claim today. 

Why These Lawsuits Matter for Women

Depo-Provera has been prescribed to millions of women over several decades. For many, it was presented as a convenient, long-term birth control option. 

The lawsuits now being filed raise important questions about whether patients were given complete and timely information about potential risks. 

In pharmaceutical cases, the issue is not simply whether a drug carries risks. The key question is whether those risks were clearly disclosed so patients and doctors could make informed decisions. 

What Compensation May Be Available

Women who qualify to file a Depo-Provera lawsuit may be able to recover compensation for: 

• Medical expenses related to diagnosis and treatment  
• Lost income or reduced earning capacity  
• Pain and suffering  
• Ongoing medical care  

These claims are intended to help individuals recover from the impact of serious medical conditions and hold manufacturers accountable where appropriate. 

What to Do If You Were Diagnosed After Using Depo-Provera

If you were diagnosed with a meningioma after using Depo-Provera, it is important to act promptly. 

Your doctor will oversee your medical care, which may include imaging such as MRI scans, monitoring tumor growth, managing symptoms, and in some cases recommending surgery or radiation treatment depending on the size and location of the tumor. 

At the same time, evidence can become more difficult to obtain over time, and legal deadlines may limit your ability to file a claim. Speaking with an attorney can help determine whether you meet the criteria for a lawsuit and what steps to take next. 

Talk to a Lawyer About Your Depo-Provera Case

If you used Depo-Provera and were later diagnosed with a cerebral meningioma brain tumor, you may have legal rights. 

The attorneys at Hissey Mulderig & Friend are investigating Depo-Provera claims and can help determine whether you qualify to file a lawsuit. 

Our law firm employs a team of female staff members, who are available to talk with you about birth control in confidence. There is no charge for a consultation, and no legal fees unless we successfully recover damages in your case. 

Find out whether you qualify or start your claim today by calling our office toll-free at 1-866-806-8117, or send us a message using our free Depo-Provera claims submission form, located at the top of this page.